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Test Code In-house NGS Request In-house NGS Request

Department

Molecular

Specimen Type

Tissue Block

Method

Next Generation Sequencing

Container

Formalin-fixed, pafaffin-embedded tissue block

Special Requirements

The Pathology case number is useful for locating the correct cell block 

Standard Volume

N/A

Ship Temperature

Room Temperature

Stability Room Temp

Up to 5 Years

CPT Code

81445, 88363

Days Test Set Up

Monday through Friday

Group Components

The Oncomine Precision Assay enables simultaneous detection of hotspot mutations (substitutions, insertions and deletions), copy number variations(CNV), and gene fusions across the following 50 cancer driver genes:

 DNA Hotspots: AKT1, AKT2, AKT3, ALK, AR, ARAF, BRAF, CDK4, CDKN2A, CHEK2, CTNNB1, EGFR, ERBB2, ERBB3, ERBB4, ESR1, FGFR1, FGFR2, FGFR3, FGFR4, FLT3, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KIT, KRAS, MAP2K1, MAP2K2, MET, MTOR, NRAS, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA, PTEN, RAF1, RET, ROS1, SMO, TP53

CNVs: ALK, AR, CD274, CDKN2A, EGFR, ERBB2, ERBB3, FGFR1, FGFR2, FGFR3, KRAS, MET, PIK3CA, PTEN

Inter-Genetic Fusions: ALK, BRAF, ESR1, FGFR1, FGFR2, FGFR3, MET, NRG1, NTRK1, NTRK2, NTRK3, NUTM1, RET, ROS1, RSPO2, RSPO3

Intra-Genetic Fusions: AR, EGFR, MET 

 

DEX code

Z03J0