Test Code JAK2B JAK2 V617F Mutation Detection, Blood
Shipping Instructions
Specimen must arrive within 7 days of draw.
Specimen Required
Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: Yellow top (ACD)
Specimen Volume: 4 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send specimen in original tube.
Forms
1. Hematopathology Patient Information (T676) in Special Instructions
2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.
Secondary ID
88715Useful For
Aiding in the distinction between a reactive blood cytosis and a chronic myeloproliferative disorder in peripheral blood specimens
Testing Algorithm
The following algorithms are available in Special Instructions:
-Erythrocytosis Evaluation Testing Algorithm
-Myeloproliferative Neoplasm: A Diagnostic Approach to Peripheral Blood Evaluation
Special Instructions
Method Name
Point Mutation Detection in DNA using Quantitative Polymerase Chain Reaction (PCR)
Reporting Name
JAK2 V617F Mutation Detection, BSpecimen Type
Whole Blood EDTASpecimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood EDTA | Ambient (preferred) | 7 days | PURPLE OR PINK TOP/EDTA |
Refrigerated | 7 days | PURPLE OR PINK TOP/EDTA |
Reject Due To
Gross hemolysis | Reject |
Other | Moderately to severely clotted |
Reference Values
An interpretive report will be provided.
Day(s) Performed
Monday through Friday
Report Available
2 to 5 daysPerforming Laboratory

Test Classification
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
81270-JAK2 (Janus kinase 2) (eg, myeloproliferative disorder) gene analysis, p.Val617Phe (V617F) variant
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
JAK2B | JAK2 V617F Mutation Detection, B | 43399-5 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
39722 | JAK2 Result | 53761-3 |
29590 | JAK2 V617F Mutation Detection, B | 43399-5 |