Test Code LEBV Epstein-Barr Virus (EBV), Molecular Detection, PCR, Varies
Test Down Notes
Effective November 27, 2024; This test is temporarily unavailable due to reagent supply issues. The down time is expected to be approximately 30 days. Order EBVPV as an alternative. See test notification here.
Necessary Information
Specimen source is required.
Specimen Required
Submit only 1 of the following specimens:
Specimen Type: Body fluid
Sources: Spinal, peritoneal, ascites, pericardial, pleural, thoracentesis, amniotic, or ocular
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Container/Tube:
Preferred: Sterile, screw cap, 5-mL aliquot tube
Acceptable: Sterile container
Specimen Volume: 0.5 mL
Collection Instructions: Do not centrifuge.
Specimen Type: Respiratory fluid
Sources: Bronchial washing, bronchoalveolar lavage, nasopharyngeal aspirate or washing, sputum, or tracheal aspirate
Supplies: Sarstedt Aliquot Tube, 5 mL
Container/Tube:
Preferred: Sterile, screw cap, 5-mL aliquot tube
Acceptable: Sterile container
Specimen Volume: 1.5 mL
Collection Instructions: Do not centrifuge.
Specimen Type: Swab
Sources: Eye and upper respiratory (nasal, throat)
Supplies:
-Culturette (BBL Culture Swab) (T092)
-M4-RT (T605)
Container/Tube: Multimicrobe media (M4-RT) and Eswabs
Collection Instructions: Place swab back into multimicrobe media (M4-RT, M4 or M5)
Specimen Type: Bone marrow
Container/Tube: Lavender top (EDTA)
Specimen Volume: 0.5 mL
Additional Information: Clotted specimens will be rejected.
Specimen Type: Tissue
Sources: Brain, colon, kidney, liver, lung, cornea, etc.
Supplies: M4-RT (T605)
Container/Tube:
Preferred: Multimicrobe medium (M4-RT)
Acceptable: Sterile container containing 1 to 2 mL of sterile saline or multimicrobe medium (M4-RT, M4 or M5)
Specimen Volume: Entire collection
Collection Instructions: Submit only fresh tissue
Useful For
Rapid qualitative detection of Epstein-Barr virus (EBV) DNA in specimens
Diagnosis of disease due to EBV
This test should not be used to screen asymptomatic patients.
Method Name
Real-Time Polymerase Chain Reaction (PCR)/DNA Probe Hybridization
Reporting Name
Epstein-Barr Virus PCRSpecimen Type
VariesSpecimen Minimum Volume
Fluids: 0.3 mL; Respiratory Specimens: 1 mL; Tissue: 2 × 2-mm biopsy; Swab: See Specimen Required
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Varies | Refrigerated (preferred) | 7 days |
Frozen | 7 days |
Reject Due To
Calcium alginate-tipped swab Wood swab Transport swab containing gel Formalin-fixed and paraffin-embedded tissues Heat inactivated specimens |
Reject |
Reference Values
Negative
Reference values apply to all ages.
Day(s) Performed
Monday through Saturday
Report Available
2 to 3 daysPerforming Laboratory

Test Classification
This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
87798
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
LEBV | Epstein-Barr Virus PCR | 23858-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
SRC67 | Specimen Source | 31208-2 |
81239 | Epstein-Barr Virus PCR | 23858-4 |