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Test Code Lupus Anticoagulant Profile, Plasma Lupus Anticoagulant Profile, Plasma

Important Note

Study should not be performed if patient is on Direct Thrombin Inhibitors (collect when patient is off medication for 72 hours); Factor Xa Inhibitors (collect after patient is off medication for 48 hours);  or Fibrinolytic agents.  If patient is on heparin, collect 5 hours post last intravenous dose or 24 hours post subcutaneous dose.  Antiphospholipids IgG/IgM are included in the profile.

If patient has been on the following medications: Angiomax(Bivalirudin), Argatroban, Refludan(Recombiant hirudin or lepirudin), Pradaxa (Dagigatran), Xarelto(Rivaroxaban), Arixtra (fondaparinux sodium); it is recommended these be discontinued for at least 72 hours prior to Lupus Screen being performed.

Department

Coagulation

Specimen Type

Plasma

Method

Optical clot based detection

Container

Sodium citrate 3.2% (light blue-top)

Special Requirements

Two (2) 2.7 mL blue-top tubes required. All tubes must be filled completely. For pediatric patients collect Two (2) 1.8 mL blue-top tubes required. Refer to specimen collection information Coagulation.

One (1) Gold top tube for adults and pediatrics.

Standard Volume

8.1ml

Minimum Volume

8.1ml

Pediatric Volume

3.6 ml

Ship Temperature

Double spun ship Frozen

Stability Refrigerated

4 hours

Stability Room Temp

4 hours

Stability Frozen

2 weeks

CPT Code

85610, 87530, 85520, 85670, 85613, 85597, 86147 x2, 86146 x2

Days Test Set Up

Monday through Friday

Group Components

Precursor Tests: PT, aPTT, Anti-Xa, Thrombin Time

Antiphospholipids: Beta 2 Glycoprotein IgG, Beta 2 Glycoprotein IgM, Cardiolipin IgG, Cardiolipin IgM

L A Screen with dRVVT (Screen), Silica Clotting Time Screen (SCT)  

L A Confirm with dRVVT (Confirm), Silica Clotting Time Confirm (SCT)

Total Normalized Screen/Confirm SCT Ratio and Total Normalized Screen/Confirm dRVVT Ratio

Pathologist Interpretation provided