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Test Code MTDNU Methadone Confirmation, Urine


Advisory Information


1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order MTDNX / Methadone Confirmation, Chain of Custody, Urine.

2. Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.

3. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Urine.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 10 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


Useful For

Monitoring of methadone treatment for analgesia or drug rehabilitation

 

Urine measurement of 2-ethylidene-1,5-dimethyl1-3,3-diphenylpyrrolidine is particularly useful for assessing compliance with rehabilitation programs.

Method Name

Gas Chromatography-Mass Spectrometry (GC-MS) Confirmation with Quantitation

Reporting Name

Methadone Confirmation, U

Specimen Type

Urine

Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

NA

Icterus

Mild OK; Gross OK

Other

NA

Reference Values

Negative

Cutoff concentrations:

 

METHADONE BY GC-MS

<100 ng/mL

 

2-ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE BY GC-MS

<100 ng/mL

Day(s) and Time(s) Performed

Tuesday through Friday; 4 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80358

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MTDNU Methadone Confirmation, U In Process

 

Result ID Test Result Name Result LOINC Value
56028 EDDP-by GC-MS 58428-4
83129 Methadone-by GC-MS 16246-1
21107 Methadone Interpretation 69050-3
21110 Chain of Custody 77202-0

Secondary ID

83129