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Test Code NSE Neuron-Specific Enolase, Serum


Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Specimens should not be transported by tube system prior to centrifugation.

2. Centrifuge and aliquot serum into a plastic vial.


Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.

Useful For

A follow-up marker in patients with neuron-specific enolase-secreting tumors of any type

 

An auxiliary test in the diagnosis of small cell lung carcinoma

 

An auxiliary test in the diagnosis of carcinoids, islet cell tumors, and neuroblastomas

 

An auxiliary tool in the assessment of comatose patients

Method Name

Homogeneous Time-Resolved Fluorescence

Reporting Name

Neuron Specific Enolase, S

Specimen Type

Serum

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Ambient  5 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject
Hemolysis at any level Reject

Reference Values

≤15 ng/mL

Serum markers are not specific for malignancy, and values may vary by method.

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
NSE Neuron Specific Enolase, S 15060-7

 

Result ID Test Result Name Result LOINC Value
NSE Neuron Specific Enolase, S 15060-7

Secondary ID

80913